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In May, the NFL sent a letter to the US Commodity Futures Trading Commission with a list of certain event contracts it deemed objectionable. By July, the league doubled down with public comments to the CFTC after the agency issued draft regulations for the contracts. The NFL cited props on player injuries, penalty totals and missed field goals as those that fit the bill. Goodell, however, conceded that the NFL has held discussions regarding prediction markets as public policy evolves.

Two other leagues, Major League Baseball and the National Hockey League, have each signed a Memorandum of Understanding with the CFTC that allows participating teams to partner with the operators.

“We don’t think we have to be first in this, we feel like we’re going to be right,” Goodell said. “The best thing to do is be patient and make sure you keep the integrity of the game number one.”

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On the surface, Week 1 appeared exceptionally bettor-friendly, as Casino.org reported.

According to LSR, NFL teams combined for 791 points—tying 2012 for the highest opening-week total ever—while setting Week 1 records for total touchdowns (93), offensive touchdowns (90), and rushing touchdowns (37). Favorites went 12-4 straight up, while the Over hit in nine of 16 games (9-6-1).

At Caesars Sportsbook, seven of eight early afternoon favorites won outright, and six games went Over the total—many hitting the mark by halftime.

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“Two of the biggest games so far this season have the Bills and the over, both in Week 1 and 2, and the Bills got there both times,” he said. “Bettors remember what teams made them money, and they’re going to keep riding them until they disappoint.”

The Bills opened their season beating the Texans in Houston 36-31, then followed that up with Thursday night’s (Sept. 17) big 41-31 home win over the Detroit Lions. Both games went over the total, and neither was particularly close.

The Bills play next Sunday (Sept. 27) at home against the 0-2 Los Angeles Chargers, with a 1 p.m. EDT kickoff.